By On Monday, October 2nd, 2017 Categories : Health


A laxative is a drug that promotes bowel actions.



Laxatives are used to save you or treat constipation. They are also used to put together the bowel for an exam or surgical operation.



Laxatives paintings in unique approaches, with the aid of stimulating colon movement, including bulk to the contents of the colon, or drawing fluid or fat into the intestine. Some laxatives paintings by way of combining those features. Bisacodyl Bisacodyl is a non-prescription stimulant laxative. It reduces quick-term constipation and is also used to put together the colon or rectum for an exam or surgical treatment. The drug works with the aid of stimulating colon movement (peristalsis); constipation is typically relieved within 15 minutes to at least one hour after management of a suppository shape and in 6 to 12 hours after taking the drug orally.


Calcium polycarbophil

Calcium polycarbophil is a non-prescription bulk- forming laxative this is used to reduce each constipation and diarrhea. It draws water to the gut, enlarging the dimensions of the colon and thereby stimulating movement. It reduces diarrhea via taking extra water faraway from the stool. This drug ought to relieve constipation in 12 to 24 hours and feature maximum impact in three days. Colitis patients must see a discount in diarrhea within one week.


Docusate calcium/docusate sodium

Docusate, a non-prescription laxative, allows a affected person avoid constipation by way of softening the stool. It works by way of increasing the penetration of fluids into the stool by way of emulsifying feces, water and fats. Docusate prevents constipation and softens bowel actions and fecal impactions. This laxative must relieve constipation inside one to three days.



Lactulose, a prescription laxative, reduces constipa- tion and lowers blood ammonia tiers. It works by using drawing fluid into the gut, elevating the quantity of water in the stool, and preventing the colon from absorbing ammonia. It is used to assist people who be afflicted by persistent constipation.


Psyllium Psyllium is a non-prescription bulk-forming laxative that reduces both constipation and diarrhea. It mixes with water to form a gel-like mass that may be effortlessly exceeded thru the colon. Constipation is relieved in 12 to 24 hours and maximum relief is carried out after numerous days.


Senna/senokot Senna/senokot is a non-prescription laxative that reduces constipation by means of promoting colon movement. It is used to deal with bouts of constipation and to prepare the colon for an exam or surgical treatment. This laxative reduces constipation in 8 to ten hours.



Recommended dosage

Laxatives can be taken by way of mouth or rectally (suppository or enema).


Bisacodyl • Adults or youngsters over 12 years: 5 to fifteen mg taken with the aid of mouth in morning or afternoon (as much as 30 mg for surgical or exam coaching). •Adult (rectal): 10 mg. • Children age 2 to eleven years: 10 mg rectally as single dose. • Children over 3 years: 5 to ten mg by means of mouth as unmarried dose. • Children under 2 years: 5 mg rectally as unmarried dose.


Calcium polycarbophil • Adult: 1 g via mouth each day, up to four times a day as wished (no longer to exceed 6 g with the aid of mouth in a 24-hour term). • Children age 6 to twelve years: 500 mg through mouth twice a day as wished (not to exceed three g in a 24-hour term). • Children age 3 to 6 years: 500 mg twice a day by means of mouth, as wished (now not to exceed 1.5 g in a 24-hour time period).


Docusate • Adult (docusate sodium): 50 to 300 mg through mouth according to day. • Adult (docusate calcium or docusate potassium): 240 mg with the aid of mouth as wanted. • Adult (docusate sodium enema): five ml. • Children over 12 years (docusate sodium enema): 2 ml. • Children age 6 to twelve years (docusate sodium): 40 to a hundred and twenty mg by using mouth in step with day. • Children age three to 6 years (docusate sodium): 20 to 60 mg through mouth consistent with day. • Children below three years (docusate sodium): 10 to forty mg by mouth every day.





FOR CONSTIPATION: • Adult: 15 to 60 ml by way of mouth each day. • Children: 7.Five ml by way of mouth each day.


FOR ENCEPHALOPATHY: • Adult: 20 to 30 g three or four instances an afternoon till stools turn out to be smooth. Retention enema: 30 to forty five ml in one hundred ml of fluid. • Infants and youngsters: Parents have to observe medical doctor’s instructions for infants and children with encephalopathy.


Psyllium • Adult: 1 to 2 teaspoons jumbled together eight oz of water  or three instances an afternoon through mouth, followed by means of 8 ounces water; or one packet in eight oz water two or three instances a day, observed with the aid of eight oz. Of water. • Children over 6 years: 1 teaspoon jumbled together 4 ounces of water at bedtime.


Senna/senokot • Adult (Senokot): 1 to 8 pills taken by means of mouth in line with day or 1/2 to 4 teaspoons of granules jumbled in water or juice. •Adult (rectal suppository): 1 to 2 at bedtime. • Adult (syrup): 1 to 4 teaspoons at bedtime. • Adult (Black Draught): three/4 ounce dissolved in 2.Five oz. Liquid given among 2 P.M. And 4 P.M. On the day prior to a scientific examination or technique.• Children: Parents need to ask their physician as dosage is based totally on weight. Black Draught isn’t always to be utilized by children. • Children age 1 month to 1 year (Senokot): 1.25 to 2.Five ml of syrup at bedtime.




The physician should be informed of any prior allergic drug response, specifically previous reactions to any laxatives. Pregnancy is also a concern. Animal studies have shown laxatives to have unfavorable outcomes on pregnancy, however no human research concerning pregnancy are currently available. These tablets are only given in pregnancy after the dangers to the fetus had been taken below consideration. Nursing mothers have to use warning and consult their physician earlier than receiving those tablets. Bisacodyl ought to no longer be administered to sufferers with rectal fissures, belly pain, nausea, vomiting, appendicitis, abdominal surgical operation, ulcerated hemorrhoids, acute hepatitis, fecal impaction, or blockage within the biliary tract. Calcium polycarbophil ought to now not receive to everyone with a gastrointestinal blockage (obstruction). Both psyllium and docusate calcium/docusate sodium have to be prevented by way of sufferers with intestinal blockage, fecal impaction, or nausea and vomiting. Lactulose must be avoided with the aid of patients who are aged, have diabetes mellitus, consume a low galactose weight loss program, or whose standard fitness is terrible. Finally, senna/senokot is inadvisable for patients with congestive heart failure, gastrointestinal bleeding, intestinal blockage, stomach ache, nausea and vomiting, appendicitis, or earlier stomach surgery.



Side results Laxatives may additionally have facet results. Some, including nausea and vomiting, are greater not unusual than others. Side outcomes related to particular laxatives are described in this segment. With repeated use, people may become depending on laxatives. All facet consequences must be mentioned to a physician.


Bisacodyl Common side outcomes: • nausea •vomiting • lack of urge for food (anorexia) • cramps Less common facet results: • muscle weakness • diarrhea • electrolyte modifications •rectal burning (whilst suppositories are used). Life-threatening: •intense muscle spasms (tetany)


Calcium polycarbophil Side consequences may encompass: •belly bloating (distention) •fuel • laxative dependency Life-threatening: •gastrointestinal obstruction


Docusate calcium/docusate sodium Side consequences include: • bitter taste inside the mouth • angry throat • nausea • cramps • diarrhea • loss of appetite • rash


Lactulose Common aspect effects encompass: • nausea •vomiting • loss of appetite •abdominal cramping • bloating • belching • diarrhea


Psyllium Common facet consequences include: • nausea •vomiting • loss of urge for food • diarrhea Less not unusual facet effects consist of: •abdominal cramping • blockage of the esophagus or gut


Senna/senokot Common side results include: • nausea •vomiting • lack of appetite •abdominal cramping Less commonplace facet results consist of: • diarrhea •fuel • urine this is red-pink or brown-black in shade • bizarre electrolyte ranges Life-threatening: •Severe muscle spasms (tetany)




Laxatives may additionally engage with other pills. Sometimes, the laxative can intervene with proper absorption of some other drug. A patient should notify their doctor or pharmacist if he or she is already taking any medications so that the right laxative can be selected or prescribed. Specific drug interactions are: • Bisacodyl: Antacids, H2-blockers, and some natural remedies (lily of the valley, pheasant’s eye, squill). • Calcium polycarbophil: (lowers the absorption of) tetracycline. • Docusate calcium/docusate sodium: Unknown. • Lactulose: Neomycin and different laxatives. • Psyllium: Cardiac glycosides, oral anticoagulants, and salicylates. • Senna/senokot: Disulfiram have to never be interested by this drug. Also, senna/senokot lowers the absorption of other drugs taken by using mouth.